PHCbi
PHC Corporation, Biomedical Division Cell & Gene Therapy LiCellGrow

Cell & Gene Therapy

LiCellGrow

Glucose and lactate in-line process monitoring
Trusted cell growth conditions

Features

Real-time Wave-mixing Bioreactor

Continuous measurement by the in-line sensors allows visualization of glucose and lactate concentration evolution

Glycolysis is one of the major energy metabolism pathways in cells. Since in this process glucose is consumed and lactate is produced, changes of their concentrations are a useful index for cell vitality. The Culture Bag is equipped with an in-line sensor, which measures glucose and lactate in real time as continuous in-line data.

Culture medium is replaced automatically based on real-time measurement and analysis

The Real-time Wave-mixing Bioreactor measures the concentrations of glucose and lactate in real-time and automatically replaces the culture medium based on the measured values. An optimal and stable supply of glucose is guaranteed and exposure to elevated levels of lactate is avoided.

Closed system cell culture with single-use Culture Bags

The dedicated Culture Bags are gas-permeable, single-use bags, each fitted with an In-Line Sensor. This system eliminates the need for sampling, greatly reducing the risk of contamination.

Highly reproducible cell culture with guaranteed sterility

The Culture Bags with in-line sensors are gamma-irradiated before supply and simply need to be fitted to the device to ensure a sterile environment for highly reproducible cell cultures.

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