Integrated Report 2026 Our Value CreationClose-Up on PHC Group’s Value Contribution Areas Executive Summary Our Value Creation Corporate Strategy Business Sustainability Data Section Appendix Value Creation Process Close-Up on PHC Group’s Value Contribution Areas Manufacturing at the Matsuyama Factory Stakeholder Engagement Monitoring (Prevention, Prognosis, & Management) Examination/Diagnosis/Treatment Research & Development PHC Group is committed to improving healthcare quality and accessibility while enhancing cost-effectiveness in three focus areas: Monitoring (Prevention, Prognosis, & Management), Examination/Diagnosis/Treatment, and Research & Development. We contribute to these areas by enabling appropriate condition management and early detection of disease, delivering accurate and rapid testing and measurement, and driving efficiencies in research practice and drug discovery. In the following pages, we explain the value we seek to create in each area, featuring the voices of PHC Group employees. Click here for an overview of the Value Creation Process By offering health checkup support services and telemedicine systems, we contribute to improving healthcare accessibility and cost-effectiveness. These solutions support early disease detection, appropriate disease management, and blood glucose monitoring for people with diabetes. Wellness (Prevention/Pre-Symptomatic Care) Wemex Health Guidance Solutions Each year, Wemex supports lifestyle improvements for approximately 210,000 people in Japan by offering health guidance solutions tailored for corporate employees who are members of health insurance associations. Approximately 210,000 People/Year Supporting healthy habits for approx. 210,000 people annually Users particularly appreciated the ability to engage in the two-way communication necessary for health guidance using contact methods tailored to each individual, such as email, LINE,* and SMS, as well as the error-checking function that streamlines claims and billing processes with insurers. * LINE is a registered trademark of LY Corporation. Hiromi YoshiokaSales Representative Preventive Medicine Promotion Section, Wellness Solutions DepartmentWemex Corporation Real-time Telemedicine System Teladoc HEALTH Teladoc HEALTH, a virtual care device for which Wemex is the exclusive distributor in Japan, is designed to enhance the accessibility of healthcare, encourage patients to seek timely consultation, and help healthcare professionals intervene remotely in potential disease progression. 32 PrefecturesAcross Japan Introduced in 32 prefectures within five years of its launch(as of the end of July 2026) Because physicians operate Teladoc HEALTH remotely, the burden on on-site staff is minimal. By connecting the system to peripheral medical devices, healthcare professionals can assess a patient’s condition with the same speed and sense of presence as if they were there in person. The system has been well received as a means of improving regional access to routine and specialty healthcare, maintaining quality of care, and supporting sustainable working practices for healthcare professionals. Naoya TsukiharaManager Business Planning Section, Hospital Solutions Department Wemex Corporation Blood Glucose Monitoring Systems Blood Glucose Monitoring Systems The blood glucose monitoring (BGM) systems provided by Ascensia empower people with diabetes to manage their condition effectively, contributing to improved comfort and quality of life. Over 3Billion BGM Sensors/Year Each year, Ascensia distributes over 3 billion BGM sensors. Healthcare professionals see value in different approaches for different patients, but we consistently hear appreciation for the accuracy, simplicity, and ease of use of CONTOUR® systems. For women with gestational diabetes, accuracy is especially important in supporting treatment decisions for both mother and baby, while features such as the smartLIGHT indicator and Second-Chance® sampling are designed with the practical needs of people managing diabetes in mind. Aldridge FriedmanRegional Sales Manager, Ascensia Diabetes Care Germany We contribute to improving the quality of healthcare and enhancing cost-effectiveness through accurate and rapid testing and measurement through clinical testing and diagnostic equipment. Additionally, we are advancing medical digital transformation (DX) initiatives, such as the adoption of electronic medical records in Japan. Clinical Testing Services Clinical Testing Services LSI Medience has partnered with 7,000 medical institutions across Japan, establishing a robust system capable of processing approximately 950,000 tests per day to support physicians in making accurate diagnoses. 120,000 Specimens/Day LSI Medience accepts more than 120,000 specimens daily from hospitals and clinics across Japan. READsystem® is a comprehensive diagnostic system for malignant lymphoma for which LSI Medience provides testing services. Malignant lymphoma is generally regarded as a challenging disease to diagnose, requiring a comprehensive assessment based not only on clinical information but also on a variety of diagnostic data, including cytogenetic and genetic analyses. READsystem® enables accurate and rapid diagnosis by simultaneously performing the necessary tests and integrating the findings through a comprehensive evaluation by highly experienced pathologists with the results of relevant diagnostic testing. The system has been adopted by numerous medical institutions throughout Japan and provides information that enhances physicians’ diagnostic efficiency and supports patients in selecting the most appropriate treatment options. Junichi TashiroShinagawa (Japan) Sales Office, Metropolitan District Branch No. 1, Sales Coordination Department, Clinical Testing Business DivisionLSI Medience Corporation Diagnostic Equipment PATHFAST™ Immunoanalyzer PHC PATHFAST™ Immunoanalyzer provides rapid, multi-parameter testing for whole blood, plasma, and serum, producing results in as little as 17 minutes to support timely decision-making in medical practice. 6Million Cartridges/Year If we were to stack all 6 million PATHFAST™ cartridges sold annually, they would reach 120 kilometers out into space. PATHFAST, which enables rapid testing using whole blood, has been praised in emergency settings for shortening turnaround time for test results. It supports rapid diagnostic decision-making and earlier patient care. Shunpei TaniguchiTokyo Metropolitan District Branch No. 3, Sales Department, Domestic Sales DivisionLife Science Business UnitPHC Corporation Pathology Diagnostic Equipment Digital Pathology Epredia’s digital pathology solutions deliver high-resolution scans of digital images, enabling precise observation of specimens on integrated screens. These systems are also capable of integrating with AI software in certain geographies and enhancing workflow efficiency. In cancer diagnostics, the final step in the digital pathology workflow is image acquisition. Epredia’s E1000 Dx Digital Pathology Solution, introduced in 2024, combines high-throughput scanning with advanced workflow management to help laboratories accelerate their transition from traditional microscopy to digital diagnosis. Together, SuperFrost™ Plus slides, SlideMate Laser technology, and the E1000 platform demonstrate how Epredia’s precision technologies work seamlessly across the pathology workflow—from specimen preparation to digital image analysis—helping pathologists deliver faster, more accurate cancer diagnoses. Dr. Balazs LipositsChief Strategy Officer & Chief Commercial Officer Epredia Holdings Ltd. Electronic Medical Record System/ Medical-Receipt Computer/Pharmacy System Medicom cloud-based EMR systemMedicom-HRf corePharnesX-MXWemex Pharmacy Management Support Wemex’s suite of solutions—including electronic medical records, medical-receipt computers, and pharmacy systems—supports medical institutions and healthcare professionals in managing clinical records and streamlining administrative tasks. Over 50,000 Over 50,000 medical institutions and pharmacies across Japan use Wemex’s medical-receipt computers. This means that one in five medical institutions and pharmacies in Japan chooses Wemex. Medicom Cloud EMR includes extensive medical-receipt checking functions and an AI-powered automated billing support function that identifies billable items from information entered in the medical record. Leveraging more than 50 years of experience in developing medical-receipt computers, this proprietary reimbursement support feature helps clinics operate and manage their practices more efficiently. Kinya MatsunagaGeneral Manager, Product Planning Department Wemex Corporation Through our life science equipment and pathology consumables, we contribute to improving the quality of healthcare and enhancing cost-effectiveness by improving the efficiency of research sites and drug discovery. Non-Clinical Testing/Clinical Trial Services Non-Clinical Contract Research Service Mediford provides a variety of testing and analysis services in Japan to ensure the safety and efficacy of pharmaceutical products available on the market. Approximately 30% Approximately 30% of the drugs approved in Japan have passed rigorous testing by Mediford to ensure their safety and efficacy. We are currently involved in pharmaceutical regulatory applications for many vaccines developed by Japanese manufacturers. We recently established a biosafety level 3 (BSL-3) facility, one of the few in Japan capable of supporting pharmaceutical regulatory submissions. Previously, obtaining the data required for regulatory submissions related to the development of vaccines and therapeutic drugs in preparation for pandemics and other public health emergencies required reliance on facilities outside Japan, but we can now conduct this work in-country. Masaki GotoImmunology & Infectious Disease Pharmacology Group, Research Unit 1, Drug Creation Innovation CenterMediford Corporation Life Science Equipment Ultra-Low Temperature FreezersCO2 Incubators PHC’s ultra-low temperature freezers and CO2 incubators are market leaders in Japan and rank second globally*1. As high-quality products, they play a vital role in supporting the value chain throughout research and manufacturing processes. All Top 20 Companies PHC is the trusted partner of all top 20 global pharmaceutical companies*2, delivering unparalleled technology and products. *1 Source: In-house research *2 Top 20 among the 50 largest revenue pharma companies in the world in 2022https://www.drugdiscoverytrends.com/2023-pharma-50-largest-companies/ These ultra-low temperature freezers maintain temperatures in the -80°C range. Their dual-cooling systems use two independent refrigeration circuits and non-HFC refrigerants, maintaining an internal temperature of -75°C even if one circuit fails. This reduces the risk of sample loss and improves energy efficiency. Maiki MoriguchiMarketing Section, Marketing Department, Biomedical Business Group, Life Sciences Business Unit, PHC Corporation The unit precisely controls the optimal temperature, CO2, and humidity for cell culture. A proprietary active humidification system maintains stable humidity and achieves rapid recovery after the door is opened and closed. This reduces the risk of culture medium dehydration and condensation, enabling researchers to achieve a culturing environment with a high degree of reproducibility. Takane OzawaMarketing Section, Marketing Department, Biomedical Business Group, Life Sciences Business Unit, PHC Corporation Pathology Consumables Microscope Slides Epredia’s microscope slides, designed to support pathologists in making efficient and accurate diagnoses, offer one of the highest levels of optical clarity on the market. Around 48 Products/Second Every second of every hour of every day, 48 of Epredia’s products are employed in the battle against cancer in laboratories and medical facilities. In cancer diagnostics, even the most advanced technologies depend on a simple starting point: the microscope slide. For almost 30 years, Epredia’s SuperFrost™ Plus slides have been the gold standard within the industry. Strong tissue adhesion is especially important in modern techniques such as H&E, special stains, and immunohistochemistry (IHC). Maintaining specimen integrity helps laboratories deliver reliable and consistent diagnostic results with the patients in mind. Dr. Balazs LipositsChief Strategy Officer & Chief Commercial Officer Epredia Holdings Ltd. Life Science Equipment LiCellMo™ Live Cell Metabolic Analyzer LiCellMo™ Live Cell Metabolic Analyzer uses proprietary high-precision In-Line sensors to continuously measure key indicators of cell metabolism without manual sampling, supporting research on cancer and stem cells. LiCellMo™ allows researchers to visualize changes in cellular metabolism in real time. High-precision In-Line sensors measure glucose and lactate, enabling users to understand and evaluate the metabolic state of cells. This supports the acquisition of metabolic data in fields such as cancer immunotherapy, including CAR-T therapy, stem cell research, and process development. Kanae SawamuraGlobal Application Business Promotion Section, Business Development Department, Biomedical Business Group, Life Sciences Business Unit, PHC Corporation LiCellGrow™ Cell Expansion System PHC’s LiCellGrow™ Cell Expansion System automatically exchanges culture media based on data from In-Line sensors that visualize metabolic changes. By constantly adjusting and optimizing the cell culture environment, it is designed to improve the quality, cost efficiency, and delivery (QCD) of cell therapy manufacturing processes. Continuous measurement using In-Line sensors enables visualization of changes in glucose and lactate concentrations. Automated culture control maintains the optimal culture environment, contributing to improved cell quality and greater process stability in manufacturing of cell therapies including CAR-T therapy. Ayano DojoGlobal Application Business Promotion Section, Business Development Department, Biomedical Business Group, Life Sciences Business Unit, PHC Corporation