Imaging and Analysis System for 3D Cell Cultures

The Unique Cell3iMager Technology

The Cell3iMager series instruments are imaging systems that capture and analyze 2D and 3D cultured cells at high-speed using SCREEN’s unique optical system and image processing technology.
Deep learning analysis allows high-confluence and non-uniform organoid images to be accurately extracted and measured. Detection of cells by their degree of differentiation and cell morphology is enabled with the Deep learning software.

Key Features

High-throughput Imager for Quantitative Analysis cells cultured in 2D and 3D environment
Cell3iMager NX

High-definition stitching with advanced image processing technology
Data integrity support, including audit trails
Multicolor Fluorescence imaging
All-in-focus images optimal for 3D cultured cell analysis can be acquired
Deep Learning for Organoid Extraction and Shape Measurement
Plate incubation function
Equipped with a variety of lenses for diverse samples

Applications

High-throughput Model
Cell3iMager NX

Multiplex assays: LIVE/DEAD Cytotoxicity
Single Cell Cloning
Cell Migration (Scratch Assay)
3D Organoid/Spheroid Morphology
Drug Screening 2D & 3D Cell Based Drug Efficacy
Drug Activity and Profiling (2D & 3D Spheroid)
Growth Rate Monitoring (2D & 3D Spheroid Assays)
"Hybridoma Cell culture"
Cell Body/Neurite Analysis
Evaluation of Anti-Angiogenics
Apoptosis Assays
Hepatotoxicity Assay
"Embryoid Body Morphology"

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Features

Cell3iMager NX

High-definition stitching with advanced image processing technology Accurate single-cell cloning analysis

Accurately analyze complex brightfield analysis such as organoids

All-in-focus images optimal for 3D cultured cell analysis can be acquired

Multiple images are captured while varying the focus in the Z direction and combined into a single image
Supports various SBS plate formats such as F-bottom, V-bottom, U-bottom, etc.

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The Cell3iMager series are manufactured by SCREEN Holdings Co.,Ltd. and marketed in North America by PHC Corporation of North America, a subsidiary of PHC Corporation in Japan.

About PHC Corporation of North America

PHC Corporation of North America, located in Wood Dale, IL, is a leader in laboratory equipment for the biopharmaceutical, life sciences, academic, healthcare and government markets. Product lines under the PHCbi brand include the space saving and energy efficient VIP® ECO and TwinGuard® ultra-low temperature freezers, cryogenic and biomedical freezers, pharmacy and high-performance refrigerators, cell culture CO₂ and multigas incubators, and Drosophila/plant growth chambers. PHC Corporation of North America is a subsidiary of PHC Holdings Corporation, Tokyo, Japan, which is a global healthcare company that develops, manufactures, sells, and services solutions across diabetes management, healthcare solutions, diagnostics and life sciences.