On-chip Sort uses a small disposable microfluidic chip (with either 80 µm or 150 µm flow channel width) as the core of its technology. Sample and sheath fluid are loaded into the sample and sheath reservoirs on the chip, respectively. Unlike conventional cell sorters, that require a specific sheath fluid, On-chip Sort allows for the use of any sheath fluid appropriate for your cells (e.g., culture medium, fresh water, sea water, oil).
Cell sorting with On-chip Sort utilizes the ‘flow shift’ mechanism. When a detected target cell is in proximity of the sorting area, a short liquid pulse is generated by pressurization of air to deflect the target cell into the collection reservoir. Non-target cells flow continuously to the waste reservoir. This sorting method does not involve the use of high pressure, nozzle, electric charges, or high-speed collision, which drive the inherent problems of other sorting techniques. More information can be found here.