TwinGuard Series Ultra-Low Freezers

We protect science so you can optimize total cost of ownership

About TwinGuard

Confidence in Every Degree

Secure, sustainable sample storage for today's pharmaceutical and biobanking needs.

PHCbi's TwinGuard Series ULT Freezers combine dual refrigeration systems for continuous protection with natural refrigerants for a reduced energy footprint. The Gen3 interface offers intuitive control and LabSVIFT® cloud integration, while advanced access options — from passwords to NFC cards and facial recognition — keep materials secure.

With stable temperature uniformity, 21 CFR Part 11 compatibility, and robust compliance support, TwinGuard is engineered to safeguard research and meet evolving sustainability standards.

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Built on Four Pillars of Protection

TwinGuard freezers feature dual cooling circuits, VIP Plus insulation, ergonomic access, and SMART lock to deliver reliable, efficient, and user-friendly sample storage.

Dual Cooling System

Independent dual circuits: TwinGuard uses two separate refrigeration systems, each with its own compressor.

Efficient operation: Only one compressor, is required to circulate refrigerant through each circuit.

VIP Plus Cabinet Insulation

Space-saving design: VIP Plus insulation maximizes interior storage volume without increasing cabinet size.

Superior efficiency: Advanced composite insulation delivers exceptional thermal performance in a compact footprint.

Ergonomic Door Handle

Smooth operation: Handle design gently pushes the door open and ensures a secure, even seal when closing.

Enhanced frost protection: Multi-point gaskets displace excess air between doors to reduce frost buildup.

Optional

Electric Lock

Track freezer access: Every access event is tracked, including door opening duration, for complete accountability.

Lock options: Electric lock with passcode, dedicated unit key, and optional NFC cards authentication and facial recognition.

Integrated Access and Frost Mitigation Design

Opening a ULT freezer can cause frost and temperature changes. TwinGuard's heated gasket helps keep the seal soft and reduces frost buildup. The EZlatch handle with built-in electric lock makes access easy and secure, with password protection standard and optional upgrades like NFC cards or facial recognition. Inner door and a curved outer door help keep cold air in and moisture out. Every door opening is tracked, showing when, how long, and how much the temperature changed, helping users protect samples and follow best practices.

TwinGuard Upright Microprocessor Controller Platform

TwinGuard Series freezers are managed by a microprocessor-based digital controller designed for setpoint security, temperature display, system status, alarm functions, and predictive performance notifications.

Data is continuously collected throughout the system to predict any deviations from expected performance that would initiate alarms with audible and visual alerts. All performance attributes are displayed and and internal time/temperature log is expressed in graphic form.

The TwinGuard LCD interface is available on TwinGuard series freezer models. On upright models, an eye-level, door mounted color LCD touchscreen allows full user control while the USB port makes transferring logged data to a PC convenient.

Performance and Reliability

TwinGuard Dual Cool Lab Freezer Performance

Superior and reliable preservation of your biological samples cannot be compromised for any reason. The primary purpose of an ultra-low temperature freezer is to protect a stored sample by achieving and maintaining uniform temperature to assure cell viability, regardless of where samples are stored. PHCbi brand TwinGuard Series ULT freezers undergo thorough temperature uniformity testing allowing us to provide our customers with temperature uniformity data that upholds our excellent performance.

Temperature Uniformity

-80°C setpoint at 23°C ambient temperature, empty freezer

Data shown reflects performance of model MDF-DU703VXHA-PA. Each line represents temperature readings taken from different interior locations within the unit. Short‑duration spikes correspond to controlled door openings that were part of the test procedure.

Data shown reflects performance of model MDF-DU503VXHA-PA. Each line represents temperature readings taken from different interior locations within the unit. Short‑duration spikes correspond to controlled door openings that were part of the test procedure.

*The data reflects performance metrics rather than official product specifications. Results from technical data sheet tests should not be used to establish regulatory parameters for specific customer applications.

The performance of the freezer will depend on factors such as the volume of customer products, storage configuration, selected options, operating conditions, test methods, and adherence to recommended maintenance practices.

Ongoing product improvements may lead to changes or omissions in this technical data sheet without prior notice. PHC Corporation of North America disclaims responsibility from damage, injury, loss, or expenses arising from the misuse of the information provided.

TwinGuard Ultra-Low Temperature Freezer Reliability

While performance is the first test of our product, long-term reliability is essential to protect your research, peace of mind, and return on your investment. The patented TwinGuard dual cool lab freezer system enhances the PHC reputation for reliability in refrigeration safety and predictive maintenance which is second to none in the world.

Two circuits work together for fast temperature recovery, while the secondary system keeps the temperature at -75°C if a service event occurs. With two independent systems each sustaining ultra-low temperatures, your samples remain safe. Users may add an optional external LN₂ backup system for additional protection.

Performance During Service Event

Performance Data TwinGuard Freezers in Case of a Service Event

Choosing Your TwinGuard Series Ultra-Low Freezer

PHCbi brand TwinGuard ultra-low temperature freezers ensure stable in-chamber temperature with twice the sample protection for double the peace of mind.


Model	MDF-DU703VXHA-PA	MDF-DU503VXHA-PA	MDF-DU303VXHA-PA
Volume	25.7 cu.ft.	18.6 cu.ft.	12.7 cu.ft.
Capacity (2" Boxes)	576	384	240
Capacity (3" Boxes)	384	256	144

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Curious about other options? Explore our full range of ULT freezers.

Learn more about the full product line of PHCbi brand ultra-low temperature freezers.

About PHC Corporation of North America

PHC Corporation of North America (PHCNA), headquartered in Wood Dale, IL, is a supplier of PHCbi life science laboratory solutions. PHCNA empowers scientific advancement by providing technologies that protect and support critical research. PHCbi solutions provided by PHCNA are trusted by researchers across the United States, Canada, and select countries in Latin America for their reliability and innovation.

PHCbi is a global leader in life science laboratory equipment, offering solutions that enhance every stage of the research workflow — from sample preservation to cell culture to regenerative medicine.

PHCNA is a proud subsidiary of PHC Holdings Corporation (TSE 6523), based in Tokyo, Japan — a global healthcare enterprise that develops, manufacturers, distributes, and services solutions across diabetes management, healthcare solutions, diagnostics and life sciences.

For more information, visit www.phchd.com/us/biomedical.