PATHFAST™ - Emergency Marker


Emergency Marker


Diagnosis of Acute Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE)

PATHFAST™ determines the quantity of hs Trop I, NTproBNP, D-Dimer, hsCRP, Myoglobin, CK-MB mass, BRAHMS PCT and Presepsin from one single whole blood sample. The quantitative data of the parallel analyses provide results within minutes, which facilitate the therapeutical decision. Basis for a safe diagnosis on-site for patients with acute coronary syndrome, suspected coronary heart insufficiency, venous thromboembolism, inflammation and myocardial injury .

PATHFAST™ D-Dimer is a chemiluminescent enzyme immunoassay for the quantitative measurement of D-Dimer concentration in whole blood or plasma. PATHFAST™ D-Dimer is used an aid in the diagnosis of activation processes of the coagulation system including deep vein thrombosis (DVT) and pulmonary embolism (PE). Plasmin-induced lysis of crosslinked fibrin results in the formation of D-dimer containing fibrin degradation fragments (XDP). D-dimer is a specific marker of the degradation of factor XIIIa- crosslinked fibrin and an indirect early marker of activation of coagulation and clot formation. The plasma concentration of D-dimer is elevated in clinical conditions associated with activation processes of the coagulation system including DVT, PE, and DIC. The exclusion of DVT or PE in patients suspicious for venous thromboembolism is possible if the D-dimer concentration is below the cut off value established by numerous clinical studies. D-dimer measurement is also usable as an aid in diagnosis and monitoring of DIC

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Assay Specifications

Method Chemiluminescent Enzyme Immuno Assay - Magtration
Sample Material - Heparin-whole Blood
- Heparin-Plasma
- Citratewhole Blood
- Citrate-Plasma
Sample Volume 100 μl
Reference Values CutOff 0.5 μg/ml FEU
Test Duration < 17 Minutes
Durability of Calibration 28 Days
Measurement Range 0.005 - 5.0 μg/ml FEU
Limit of Detection 0.005 μg/ml FEU
Pack size 60 tests

* for more detailed information, please refer to the instruction for use, delivered with each reagent