Diagnosis and prognosis (antibiotic stewardship) of sepsis
PATHFAST™ determines the quantity of hs Trop I, NTproBNP, D-Dimer, hsCRP, Myoglobin, CK-MB mass, BRAHMS PCT and Presepsin from one single whole blood sample. The quantitative data of the parallel analyses provide results within minutes, which facilitate the therapeutical decision. Basis for a safe diagnosis on-site for patients with acute coronary syndrome, suspected coronary heart insufficiency, venous thromboembolism, inflammation and myocardial injury .
PATHFAST™ B･R･A･H･M･S PCT is an immunoassay for the in vitro quantitative determination of Procalcitonin (PCT) concentration in whole blood, plasma or serum. PCT is used as a marker of host response to bacterial infection. PATHFAST™ B･R･A･H･M･S PCT is used as an aid in the early detection and differential diagnosis of clinically relevant bacterial infections, in the assessment of the degree of septic severity and in the risk stratification of the outcome of patients with systemic bacterial infection, sepsis, severe sepsis and septic shock. PATHFAST™ B･R･A･H･M･S PCT is also used as an aid in decision making on antibiotic therapy for patients with lower respiratory tract infections (LRTI) and in decision making on antibiotic discontinuation for patients with suspected or confirmed sepsis. PCT is used as an aid in the diagnosis of sepsis, severe sepsis and septic shock in systemic inflammatory response of bacterial infection as well as in the assessment of the degree of septic severity and to aid in the risk stratification of critically ill septic patients. PCT has shown to be useful in decision making to initiate to monitor and stop antibiotic treatment in randomized controlled clinical studies in patients with acute respiratory tract infections and sepsis. PCT is also useful as an antibacterial drug index to prevent severity from lower respiratory tract infection to sepsis.
Advantage of PATHFAST™ B·R·A·H·M·S PCT
Due to its reagent design and reagent throughput, PATHFAST™ is designed as an optimal companion combining the quality of results of a central lab analyser with the flexibility of a point of care testing device in one instrument. The PATHFASTB·R·A·H·M·S PCT assay can either complement the central lab patient testing or simply can be placed into the ED/ICU in order to perform rapid and reliable patient assessment at the point of care. The ability to use whole blood samples provides multiple options to enhance the diagnostic power for sepsis patients.
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